Funny, I was actually typing out a rant earlier about how so much of the indie web is inaccessible in many forms (specifically about sites where content is blocked by divs and images and hard to access. If I can zoom out and see all of the content, I still consider that to be accessible). Like, I primarily use my laptop, but if I'm at work, I'll use my phone, and many sites are unintelligible on mobile.
Really, the big pet peeve I have is the flashing lights and images. I'm not epileptic, nor am I photosensitive, but so many sites give me a headache when I visit them.